Journal: Biology Direct
Article Title: Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence
doi: 10.1186/s13062-021-00292-9
Figure Lengend Snippet: Long (ϕ 1 ) and short (ϕ 2 ) fluorescence correlation lifetimes of apo-wt and apo-mutants (blue) aromatase. The values of ϕ 1 and ϕ 2 upon the addition of substrate or inhibitor are reported in green and red, respectively. In the cartoons, a ribbon model of aromatase is reported in which the positions of R264 and of the five tryptophans are highlighted in green and pink VDW spheres
Article Snippet: Fluorescence spectra were collected using a K2-ISS (ISS, Inc.,Champaign, IL, USA) photon-counting fluorimeter thermo-stated at 20 °C using an external bath circulator.
Techniques: Fluorescence